Word: dieting
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Dates: during 1990-1999
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This is the season when Americans gingerly try on bathing suits before bedroom and dressing-room mirrors and wish there were a diet pill that would erase those fleshy bulges. They may never get their wish, but they may be getting closer. Last week the U.S. Food and Drug Administration approved a new antiobesity drug called dexfenfluramine that will be sold in America perhaps as early as June by Wyeth-Ayerst under the brand name Redux. It is the first diet drug approved for use in the U.S. in the past 23 years and represents a new generation of smarter...
...Diet pills got a bad name in the '70s, when doctors prescribed amphetamines (a.k.a. "speed") and their patients became addicted. Unlike amphetamines, which burn up extra calories by jacking up the body's metabolism, dexfenfluramine gets people to eat less food by shutting off appetite. It does this by triggering the release of serotonin, a brain chemical that induces feelings of fullness and satisfaction...
...weight control that reflects medicine's new understanding of obesity as a chronic disease rather than a failure of willpower. "Some people will need to take [weight-control] medications all their life, just as some need to take medication for hypertension," says Dr. Michael Hamilton, director of the Duke Diet and Fitness Center at Duke University. That could be an expensive proposition: a month's worth of Redux is expected to cost $75. Some who can improve their eating and exercise habits, Hamilton suggests, may eventually be able to wean themselves from the pills...
...expected to approve more diet drugs in the next few years. Knoll Pharmaceutical's sibutramine is a serotonin drug, like dexfenfluramine and its predecessor, fenfluramine. Roche Laboratories' orlistat uses a different approach: it binds to food in the intestines, blocking the absorption of about one-third of dietary...
...raining in Sydney, Australia, and Franklin Graham is nervous. Once he might have slugged back a Scotch; now a diet Coke will have to do. It is always tough being a stand-in, and worse still if you're substituting for a legend. In fact, when illness forced his father out of this series of revival meetings, the organizing committee in Sydney simply dissolved itself. Ultimately another group decided to take a chance on Franklin but moved the revival from a downtown venue that could have held 50,000 people to an open, grass amphitheater--no seats, just turf--with...