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...data make clear that there are almost no genes that are exclusively expressed in any one structure or region. That, says Allan Jones, chief scientific officer of the Allen Institute for Brain Science, means "people will have to think harder about targeting pathways with combinations of drugs." Researchers like Dietrich Stephan at the Translational Genomics Research Institute are doing just that. Relying on the ABA, Stephan has identified a group of genes involved in age-related memory loss and has developed five compounds that mimic the activity of the genes. At least three of the new compounds appear to enhance...

Author: /time Magazine | Title: The Brain: What The Mouse Brain Tells Us | 1/19/2007 | See Source »

...London's Carbon Clear, say they invest not just in planting trees, but also in ensuring they thrive. But others may not be so diligent and disease, fire and logging can all shorten a tree's life. "You can never be sure the atmosphere sees the benefit," says Dietrich Brockhagen, managing director of atmosfair, a Berlin-based offset provider that avoids reforestation schemes...

Author: /time Magazine | Title: Lost in the Forest | 1/9/2007 | See Source »

...many people have forgotten that CO2 is a basic need for the earth's vegetation. More CO2 increases plant growth and harvests. The fight against carbon emissions and climate change is nothing but ideological and political hype. This will become apparent when the next and inevitable cooling period occurs. Dietrich E. Koelle Ottobrunn, Germany If the world is waking up to the reality that global warming is here (not a future event) and wishes to take effective action, we need to listen to voices other than those who insist that economic activity must be curtailed. The way forward lies...

Author: /time Magazine | Title: Outstanding European Individuals | 11/28/2006 | See Source »

...Somehow, decades after her brief fame, in a last-minute rescue so late it was nearly post-mortem, Brooks triumphed. In 1953, Henri Langlois of Paris' Cinematheque Francaise spearheaded the revival of her reputation by proclaiming, "There is no Garbo! There is no Dietrich! There is only Louise Brooks!" The cue for his effusion was George Wilhelm Pabst's 1929 German melodrama Pandora's Box, in which Brooks plays Lulu, an innocent beguiler who radiates sexuality so unself-consciously toxic that it drives men mad - beyond lust, to disgrace and murder...

Author: /time Magazine | Title: Lulu-Louise at 100 | 11/14/2006 | See Source »

...Pabst, who was close to hiring Marlene Dietrich before Brooks said yes, knew that the Germans would be outraged that an American flapper was playing their Lulu, a character that was nearly a national icon. (Imagine the flap in Britain if this were announced: Brad Pitt is James Bond.) But they couldn't resist Brooks' fresh approach, which painted Lulu as a naif with bad taste in beaux. A carnal Candide, a blithe arsonist of men's hearts, she has no calculation in her, just a knowing or beckoning smile. Her face makes a kind of smile when...

Author: /time Magazine | Title: Lulu-Louise at 100 | 11/14/2006 | See Source »

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