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...endemic in the developing world is starved for resources. The World Health Organization estimates that 90 percent of the world’s health-related research addresses only 10 percent of global disease burden, leaving many diseases neglected by the modern research enterprise. These “neglected tropical diseases?? (NTDs) include schistosomiasis, trypanosomiasis, hookworm, cholera, and malaria, and account for nearly a million and a half deaths per year...

Author: By Matthew F. Basilico and Jason Zhang | Title: Stepping Up Harvard's Leadership in Global Health | 4/10/2008 | See Source »

...diseases caused by bacteria such as pneumococcus, which can cause everything from ear infections to pneumonia. The vaccines’ capacity to protect against a variety of diseases at once makes them particularly valuable in developing parts of the world. The only such vaccine currently available to fight these diseases??Prevnar, produced by the pharmaceutical company Wyeth—remains too costly for the developing nations that are most affected. According to Mekalanos, the new technique is inexpensive enough to be used even in poor countries. The Morningside Group, a Chinese company, holds the distribution rights...

Author: By Benjamin M. Jaffe, CONTRIBUTING WRITER | Title: HMS To Increase Vaccine Access | 10/15/2007 | See Source »

...Gates also said that while it would take decades before vaccine research for diseases??including AIDS—would materialize, efforts can still be made in the meantime to prevent risky behavior in developing parts of the world...

Author: By Kevin Zhou, CRIMSON STAFF WRITER | Title: Gates Delivers Speech to Graduating Class | 6/7/2007 | See Source »

...cheek cells left on the candidate’s utensil, he carries the gene that causes Huntington’s Disease, a fast-acting, highly degenerative neurological disorder that first appears in the patient’s middle-aged years. Doctors say chances are high that the diseases?? onset will come within the next five years. Under heavy pressure, he withdraws from the race, since there’s a good chance that he’d be unable to complete a term as president...

Author: By Matthew S. Meisel | Title: The Public Genome | 4/27/2007 | See Source »

...What would be far more useful, however, is to know individual patients’ exact genomes. Why? First, it would allow physicians to screen patients’ entire genome for gene variants that predispose us for certain diseases??instead of ordering a volley of individual (read: expensive) tests for different disorders. Women who carry a gene variant known to increase breast cancer risk, for example, would be able to begin mammograms earlier in life. Second, it would allow physicians to personalize medical treatments. In a few cases, this is already possible. The breast cancer drug Tamoxifen is much...

Author: By Matthew S. Meisel | Title: The Public Genome | 4/27/2007 | See Source »

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