Word: dish
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Dates: during 1990-1999
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Restaurant Zinc's signature creation is itsZinc platter, a towering two-story dish ofoysters, clams, crab claws, shrimp and lobster...
...that they don't want to pass on to the next generation, they can opt for a remarkable procedure called pre-implantation genetic diagnosis (PGD). It starts with standard in-vitro fertilization, in which sperm from the father are mixed with eggs collected from the mother in a Petri dish. Then comes the genetic magic...
...nothing more than a tiny strip of DNA or RNA crammed into a protein envelope. Using the tools of molecular biology, scientists render the virus harmless by deleting some or all of its genes, splicing the therapeutic gene into the remaining genetic material and, in a laboratory Petri dish, mixing it with human cells. The altered virus, now called a carrier or vector, can deliver the therapeutic gene into the nucleus with great dispatch...
...spectacular things with cells in a laboratory dish," explains Anderson. "You can easily get the genes in, change the cell's properties and do other things that ought to enable you to treat disease successfully." That is precisely what Anderson and his colleagues did eight years ago in the first approved use of gene therapy, when they removed blood cells from a young patient, genetically altered them with a viral vector and infused them back into her bloodstream...
That scenario is not as farfetched as it sounds. Talk to anyone in the pharmaceutical industry, and you'll soon discover that genetics is the biggest thing to hit drug research since a penicillium mold floated into Alexander Fleming's petri dish. Sure, scientists have long known genes play a role in almost every ailment from Alzheimer's to yellow fever. But it is only in the past few years that they've learned how to use that information to identify a multitude of new targets and pathways for drug design. Let's count the ways...