Word: dna
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Dates: during 2000-2009
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...paper featured this week on the cover of the journal entitled “Science”, the researchers reported two major findings that contributed to answering how our cells stowed three billion base pairs of DNA while maintaining access to functionally crucial segments...
First, the scientists discovered that human genome is divided into two separate compartments of active genomes and unused DNA...
Chromosomes repeatedly snake in and out of the two compartments as their DNA alternates between active, gene-rich and inactive, gene-poor stretches...
Second, scientists observed that DNA was compressed into an architecture called a “fractal globule?...
This configuration deviates from the previously-proposed configuration of an “equilibrium globule”, and allows cells to pack DNA incredibly tightly while avoiding knots and tangles that might interfere with the cell’s ability to read its own genome...