Word: dna
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...intended: malnourished children of the developing world. And that, he knew, was not likely to be easy. Why? Because in addition to a full complement of genes from Oryza sativa--the Latin name for the most commonly consumed species of rice--the golden grains also contained snippets of DNA borrowed from bacteria and daffodils. It was what some would call Frankenfood, a product of genetic engineering. As such, it was entangled in a web of hopes and fears and political baggage, not to mention a fistful of ironclad patents...
...beta amyloid exploded. Researchers had long been aware that early-onset Alzheimer's, while rare, often ran in families. Could it be, they wondered, that the culprit was a mutant version of the APP gene? In 1991 scientists at London's St. Mary's Hospital Medical School screened the DNA of an Alzheimer's family and found what every geneticist in the field had been furiously looking for. The mutant APP gene sat on chromosome 21, and the single change in its DNA sequence occurred in the vicinity of the beta-amyloid fragment...
...been randomly sampling and sequencing small bits of cDNA. But one of his new recruits, Hamilton Smith, a Nobelist from Johns Hopkins', proposed a bolder approach: "shotgunning" the entire genome of an organism. The idea was dramatically simple. Using an ordinary kitchen blender, they would shatter the organism's DNA into millions of small fragments, run them through the sequencers (which can read 500 letters at a time), then reassemble them into the full genome using a high-speed computer and novel software written by in-house computer whiz Granger Sutton. By contrast, the HGP divided the genome into larger...
...stay of execution with compassion for Ricky Nolen McGinn [NATION, June 12]? Bush has always been a man-eating tiger about Texas executions. Do we think a catchy campaign phrase can suddenly change his stripes? You didn't report that Barry Scheck offered to pay for a DNA test for McGinn, who was convicted of rape and murder. The fear of being caught with a wrong decision is what drives most politicians of any stripe. PHIL PARKINSON Rio Rancho...
That George W. Bush just plain irritates Margaret Carlson is clear. Give the man a break. Bush showed strength and courage by allowing a condemned man some extra time to complete DNA testing. DENNIS HANSEN Houston...