Word: dna
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...than Sam.) Turns out that SAM or SAMe plays a pivotal role in hundreds of biochemical reactions in the body. It's a methyl donor, meaning that it can attach a molecule made of one carbon atom and three hydrogen atoms to various proteins, lipids and even snippets of DNA. Such methylation reactions are important in the production of many critical substances, including neurotransmitters in the brain and enzymes that help repair joints and the liver...
...Broadway musicals intent on offering messages instead of laughs, it's no wonder that comedy-starved audiences have been flocking to off-Broadway revues. Spotlighting mankind's tics and follies, composer-lyricist John Forster has created the freshest and funniest of them. Whether targeting the timely (Thomas Jefferson's dna) or the timeless (romantic mismatches), Forster delivers hilariously. The cast of five is just about perfect...
...occurred to him, he told police there, that he had cut his finger to the bone during the summer before his wife's murder. If there was any blood in the car, he insisted, it was his own. But Barton refused to give blood or saliva samples for DNA testing or take a lie-detector test. In the end, the authorities had strong feelings Barton was guilty, but there were no witnesses to place him at the campground, no fingerprints and only inconclusive forensic evidence. Before they could retest the blood traces in his car, Barton claimed to have spilled...
Scientists have known for more than two decades that cancer is a disease of the genes. Something scrambles the Dna inside a nucleus, and suddenly, instead of dividing in a measured fashion, a cell begins to copy itself furiously. Unlike an ordinary cell, it never stops. But describing the process isn't the same as figuring it out. Cancer cells are so radically different from normal ones that it's almost impossible to untangle the sequence of events that made them that way. So for years researchers have been attacking the problem by taking normal cells and trying to determine...
...According to a report in the current issue of Nature, a team of scientists based at M.I.T.'s Whitehead Institute for Biomedical Research has finally managed to make human cells malignant--a feat they accomplished with two different cell types by inserting just three altered genes into their DNA. While these manipulations were done only in lab dishes and won't lead to any immediate treatment, they appear to be a crucial step in understanding the disease. This is a "landmark paper," wrote Jonathan Weitzman and Moshe Yaniv of the Pasteur Institute in Paris, in an accompanying commentary...