Word: dogged
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...understand how the credit crunch is hitting American business - and, in turn, you - look no further than the Dog Shop, a pet-supplies and -grooming store in Washington, D.C. This holiday season, owner Jane Huelle will stock only four varieties of Christmas-cookie dog treats instead of the usual six. That's because a month and a half ago she got a letter from her credit-card company saying her line of credit was being docked by thousands of dollars...
...Huelle hadn't done anything wrong - she never missed a payment, and her credit score was unchanged - but tighter lending standards across the board meant the safety net she'd counted on for emergencies (a dog-dryer breakdown, say) was suddenly that much smaller. Now, as a precaution, she's cutting outlays, including the money she spends on inventory. "The banks are looking at everyone with a fine-tooth comb," she says. "In terms of the consumer, they're not going to have the same selection or quantity they would have otherwise...
...surveyed chief financial officers at 100 large retailers and found that 41% had experienced a tightening of credit by their lenders. That finding was set right next to another: that 37% of retailers planned to reduce inventory purchases for the rest of the year. Sounds like Jane Huelle's Dog Shop all over again...
British forecaster EvaluatePharma says Roche is on track to take over as Big Pharma's top dog by 2014, up from No. 5 today. But it won't get there without a fight. Crosstown rival Novartis is also revamping how it does R&D and holds a 13% stake in Alnylam. U.K. concern GlaxoSmithKline already underwent its own re-engineering, and the results are evident. In 2000 its pipeline had two major prospects; now, stocked with 34 late-phase drugs on the horizon, it appears to be one of the industry's healthiest...
...esteem issues. As almost any woman - from the head of the Budgerigar Breeders association to Queen Elizabeth - can attest, it's almost impossible to get confidence right. Too timid and you're a pushover. Too self-aggrandizing and you're a bad word unless it's about a dog, or Project Runway's Kenley. Or Michelle, my best friend until 9th grade, after she won that debating prize and got cocky...