Word: domagk
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...technical talent, especially in a chemist named Ernst Boris Chain, who had fled Nazi Germany. Armed with funding from the Rockefeller Foundation, these scientists made it their objective to identify and isolate substances from molds that could kill bacteria. The mission was inspired by the earlier work of Gerhard Domagk, who in 1935 showed that the injection of a simple compound, Prontosil, cured systemic streptococcal infections. This breakthrough demonstrated that invading bacteria could be killed with a drug and led to a fevered search in the late 1930s for similar compounds. Fleming's Penicillium notatum became the convenient starting point...
...contribution changed the practice of medicine. He deserves our utmost recognition. At the same time, we must bear in mind that the "Fleming Myth," as he called it, embodies the accomplishments of many giants of antibiotic development. Fleming is but a chosen representative for the likes of Florey, Chain, Domagk, Selman Waksman and Rene Dubos, many of whom remain, sadly, virtual unknowns. Their achievements have made the world a better, healthier place. In commemorating Fleming, we commemorate them...
Died. Gerhard Domagk, 68, German chemist who in 1932 discovered that sulfonamides cured infection, thereby creating the first "wonder drugs"; of a heart attack; in Konigsfeld, West Germany. Domagk was research director for I. G. Farben when he found some textile dyes stopped infections in mice, successfully applied a dye to his daughter's infected finger, later isolated the active ingredient, a sulfa compound he called prontosil-an achievement that won him a 1939 Nobel Prize, which Hitler, piqued with the Nobel committee at the time, forced him to refuse...
...educational theories. It was wonderful." As a boy. he grew mushrooms in the family cellar, cultivated molds in his mother's fruit jars. In 1929 the famed Pasteur Institute of Paris offered Biologist Bovet a job. By 1932 news reached Paris that Germany's Gerhard Domagk had found that a dye product, prontosil could be used to kill bacteria that cause common infections. Bovet and his colleagues at the Pasteur found that prontosil was "a clumsy, complex chemical," set about breaking it down. After months of night-and-day work they found the essential germ killer...
Meanwhile, in West Germany's Bayer Institute for Experimental Pathology, other researchers read his reports on the drug's selective toxin. Directed by another Nobel Prizewinner, Professor Gerhard Domagk, the Germans took up where Waksman left off. Working with fungus cultures, they isolated actinomycin C, a new form of the original antibiotic...