Word: domagk
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...chemical was showing promise in treating tuberculosis, they got an eye-opener. The drug had passed the promising stage, had shown impressive results over a two-year period in the treatment of 7,000 patients. And behind its discovery and development was the potent name of Professor Gerhard Domagk, 54, who won fame-and a 1939 Nobel Prize, which the Nazis would not let him take-as top man in perfecting the sulfa drugs...
Professor Domagk had found that the thiosemicarbazones were active against the tubercle bacillus and against no other germs (hence the name Tibione, derived from T.B. One). Because streptomycin and P.A.S. were hard to get in dollar-short Europe, German doctors used cheap-to-make Tibione lavishly on all kinds of tuberculosis sufferers...
...hiatus might not have been so long if during that period Germany's Gerhard Domagk had not discovered sulfa drugs (TIME, Dec. 28, 1936), which began to save lives so dramatically that the experts dropped everything else to test them out. In 1933, Dr. Fleming himself lent a hand with M & B 693, also known as sulfapyridine. The sulfas almost seemed to be the dream drugs he had looked for. They stopped deadly streptococci, even cured pneumonia. But the more sulfa drugs were used, the clearer it became that they 1) sometimes delayed healing by irritating wound walls...
Without any real understanding of how sulfa-drugs overcome infections, doctors have been freely using them ever since Dr. Gerhard Domagk of Germany discovered prontosil, forerunner of sulfanilamide, in 1932.* But the mystery of their effectiveness has recently been cleared up by a series of discoveries reviewed in a recent issue of the British Medical Journal...
...frown from the Nazis, Domagk rejected a $40,000 prize from the fund established by the peace-loving inventor of dynamite, Alfred Nobel...