Word: donors
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...Mass General and Harvard who led the study, is to prepare a patient's immune system well before the surgery?or, to be more exact, to deplete the immune system's T cells, which normally patrol the body looking for foreign invaders like bacteria, viruses and tissues from outside donors. Several days before the transplant surgery, Sachs' team used drugs that target and eliminate these cells to wipe the immune slate clean. Then the team transplanted the kidney along with donor bone-marrow cells. What happened next was surprising: the bone marrow rebuilt the immune system but this time...
...retrains the immune system, fooling it into thinking that the donor tissue is now part of the self," says Sachs. One patient was able to stop taking antirejection drugs as early as nine months after his surgery?though not without some discomfort as the body adjusted. "There is no question that during the initial phase, the patient has a lot more difficult time. But they trade that difficulty with what is beginning to look like lifelong suppression [of rejection]," says Sachs...
...original version of this article mistakenly reported that surgeons transplanted a donated kidney along with bone-marrow cells that had been harvested from the patient. In fact, the bone-marrow cells also came from the donor...
Though the properties were given to Harvard specifically for faculty use, the University argued in court filings that the “costs of maintaining Kendall have become prohibitive,” and that the maintenance fund provided by the donor, William M. Kendall, covered less than half of the total cost of keeping up the property...
...waiting for organs. Probably not, says the University of Oklahoma's Dr. Mark Fox. "Since people have the opportunity to opt out, it seems like it's consistent with freedom of choice," Fox says. "But to force someone to say, 'I don't want to be an organ donor' is potentially coercive...