Word: dose
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Dates: during 1990-1999
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...made chemical at any dose causes cancer in laboratory animals, the law says it can't be used as a food additive. But a wide variety of naturally occurring chemicals, found in all sorts of foods, can cause cancer in animals as well. A team of researchers from the University of California, Berkeley, and the Lawrence Berkeley Laboratory has tested 80 such natural carcinogens. Its conclusion, reported in Science, is that natural chemicals may be significantly riskier than artificial ones. Among the foods that cause problems: wine, lettuce, apples, mangoes and whole-wheat toast...
Furthermore, doctors have learned that a given dose of morphine packs more punch when combined with local anesthetics like Bupivacaine or with the newest nonsteroidal anti-inflammatory drugs (the category to which Tylenol and aspirin belong). That strategy also helps patients avoid the side effects of opiates, such as nausea, constipation, hallucinations and itching...
...breakthrough idea in acute-pain management today is titration -- the precise tailoring of dosage to the needs of a particular patient. There is, quite simply, no such thing as a standard dose anymore. Doctors have grudgingly come to recognize that the patient is the best judge of how he or she feels. Today people in acute pain can control their own medication with PCAs, or patient-controlled analgesia. These are digital pumps that are connected to a catheter. Physicians set a base amount of drugs that enter the body continuously. When pain increases, the patient can push a button...
...abortions. But a new study done at the University of Edinburgh shows that the drug actually prevents pregnancy in the first place. If taken within 72 hours after intercourse, the drug keeps a fertilized egg from implanting in the uterus. The same happens if a woman takes a high dose of birth-control pills, but RU 486 has fewer side effects. As an editorial in the New England Journal of Medicine points out, the use of RU 486 could cut down on the number of abortions, since it's technically a contraceptive...
...common belief among the pepperati nowadays is that a dose of hot chile, while not strictly medicinal, stimulates the senses and clears the mind, prodding the palate to the threshold between pleasure and pain. There are even some aficionados who tell of a "chile high," produced by the body's endorphins in reaction to the sting of the pepper...