Word: dose
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Dates: during 2000-2009
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When they started work on The Bourne Supremacy in Moscow in 2003, Greengrass repaid his star with a priceless dose of artistic freedom. While filming a scene in which Bourne had just been shot, Damon was supposed to touch his shoulder, look at the blood on his hand and keep moving. "We were losing the light, and I was walking through this little tunnel," Damon remembers. He tried to position his arm in a way that would help the cameraman get his shot in time. "I didn't want to hold my bloody fingers below his frame. Paul came running...
...virginity are rife in Indonesian films, because those are the images that draw the kids to the theaters. In most cases, films are made for less than $500,000, and producers need to sell at least 300,000 tickets to break even. Few reach that benchmark without a heavy dose of teen romance, superstition or horror, and even then most Indonesian films aren't shown for more than a week on a particular screen. "The only films that do well now are ones kids see over and over," adds producer Wijaya. That's a formula Hollywood knows all too well...
Fortunately for these young patients, however, the strategy turns out to be extremely effective. Simply increasing the dose of certain agents, for instance, gives kids an advantage over some rapidly growing cancers. Young hearts, lungs and kidneys, it seems, are fairly resilient and can be bombarded with higher doses of toxic drugs than most adults can tolerate. And better medications for handling the side effects and consequences of chemotherapy and radiation--severe nausea, vomiting, anemia and infections--help children respond better to intensive treatment...
...question clinicians will need to consider is whether the benefits of CTCA outweigh the risks. In absolute terms, the lifelong attributable risk of cancer per CTCA scan was low, ranging from 0.02% (for an 80-year old man, with the dose-reduction strategy) to 1% (for a 20-year-old woman, with a regular heart and aorta scan). The benefits of CTCA are that it is noninvasive, quick (the test takes about 10 minutes), requires that the patient ingest less contrast dye than with other scans and can be performed immediately in an emergency room when someone is admitted with...
...Down the line, Einstein believes his team's conclusions will boost cardiac diagnostic technology and prompt major manufacturers to improve it. "This is an impetus toward accelerating the pace of research in cardiac CT scans so as to reduce the dose to patients," says Einstein...