Word: dose
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...this can be especially powerful. Any significant experience triggers changes in brain genes that produce proteins - those necessary to help memories form, for example. But, says the study's lead author, Ian Maze, a doctoral student at Mount Sinai School of Medicine, "when you give an animal a single dose of cocaine, you start to have genes aberrantly turn on and off in a strange pattern that we are still trying to figure...
Increases in the number of these spines can reflect learning. But in the case of addiction, that may involve learning to connect a place or a person with the desire for more drugs. Maze showed that even after a week of abstinence, mice given a new dose of cocaine still had elevated levels of gene activation in the nucleus accumbens, meaning G9a levels were still low. It is not known how long these changes can last. Maze also showed that when he intervened and raised G9a levels, the mice were less attracted to cocaine...
When you need relief from that cold or cough, do you use a spoon to measure the quantity? If you do, you're like millions of people - and like them, you're probably taking the wrong dose...
...perils of acetaminophen can be particularly acute for two groups: drinkers - whose livers may already be working overtime - and kids. Unlike doses for adults, those for children tend to be very precise, right down to the milligram, which means even a single, small overdose is something to be avoided. Even more confounding is the counterintuitive way in which the formulation of a drug for infants can differ from that for an older child: the infant's version can actually be stronger since it is often administered in tiny amounts with a medicine dropper. "We've done studies here that show...
...fact, a "normally functioning joint can withstand and actually flourish under a lot of wear," says Fries. Because cartilage - the soft connective tissue that surrounds the bones in joints - does not have arteries that deliver blood, it relies on the pumping action generated by movement to get its regular dose of oxygen and nutrients. "When you bear weight, [the joint] squishes out fluid, and when you release weight, it sucks in fluid," says Fries, explaining why a daily run or any other workout is useful for maintaining healthy cartilage...