Word: dosing
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Dates: during 1960-1969
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Such stereotyped prescribing is extremely unsound, says Pharmacologist Sumner Kalman of Stanford University. "There is no average man who always needs a particular dose of this or that drug on a certain daily schedule," Dr. Kalman notes. Even patients who are identical in sex and size do not absorb a drug into the bloodstream at the same rate. Their systems do not metabolize the drug at the same rate. Moreover, their reactions to a drug may range all the way from nil to collapse and sudden death as a result of severe allergic shock. "The fate of a drug...
Heroin is usually injected directly into a vein or "mainlined," and it soon slows down vital functions. A large enough dose will stop them altogether. Yet it is often difficult to determine the exact cause of death. Dr. Milton Helpern, New York City's chief medical examiner, says that there is no clear evidence of simple overdose in the great majority of heroin deaths. Instead, 90% are caused by what he calls an "acute reaction" to the drug or its adulterants. "We don't like to call them overdoses...
Even when the heroin dose is not strong enough to cause sudden death, its depressive effect on the respiratory system can bring on severe lung congestion resulting in death within a few hours. Most other heroin deaths are due to viral or bacterial infections carried by the needle. These infections include endocarditis, an inflammation of the heart valves, tetanus, which kills few people aside from addicts nowadays, and viral hepatitis...
...months, three groups of albino rats at a Texas Tech University laboratory were given some musical entertainment. One group of newborn rat pups was exposed to selections from Mozart-The Magic Flute, Symphonies 40 and 41, the Violin Concerto No. 5. A second group audited an equivalent daily dose of Arnold Schoenberg-Pierrot Lunaire, Verkldrte Nacht and Kol Nidre, among other compositions. The third set of rats, appointed as a control, heard nothing but the whirring of a ventilation...
...year's 10% income tax surcharge was covered by their withholding taxes. The federal budget will soon shift to a slight surplus after three years of inflationary deficits. At this point, top Administration officials figure that present measures will begin to bring inflation under control-perhaps without another dose of higher interest rates...