Word: dosing
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Dates: during 1990-1999
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...Mart is retailing's biggest fixer-upper, and Stewart, author of laborious decorating tips and arbiter of God-is-in-the-details perfectionism, is in the midst of injecting it with a large dose of the upper-crust life-style that is Martha Stewart living. In a joint venture with K Mart, Stewart has launched a signature paint (with Sherwin-Williams) and home collection: Martha Stewart Everyday, the first salvo in an all-out assault on K Mart's style sensibility. If Stewart has her way (and she usually does), America will soon be changing its sheets the Martha...
...because other doctors began to seek them out. One of their first cases was an 18-year-old boy with cancer. Suddenly, the boy's pain had spun out of control. "In three days he went from no morphine to 400 milligrams an hour, which is a pretty industrial dose," says Berde. "A normal amount might be 3 milligrams an hour...
...Among the techniques: cryosurgery to freeze tissue to be removed, or use of a harmonic scalpel, a vibrating laser that simultaneously cuts tissue and clots blood. Brain surgeons treating tumors and repairing blood-vessel malformations are also using a state-of-the-art gamma "knife" that delivers a high dose of radiation to precise points in the head through tiny holes in a helmet that resembles a salon hair dryer...
...degree. "The fantastic thing about bradykinin," says Black, "is that it does not open the barrier to the normal brain--only to tumors." By using RMP-7, a synthetic version of bradykinin, Black's team has been able to focus chemotherapy drugs right on the tumors, increasing the effective dose as much as 10-fold. Crucial to RMP-7's success, however, is the development of more effective chemotherapy drugs against brain cancer...
While the defense has been glued to the television watching a heavy dose of film starring Abdullah and a supporting cast of nifty bootlegs and playaction schemes intended for the speedy Braswell, the offense has found little need to tailor a specific strategy for the game...