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...same time, hints that the drugs could make anyone - not just depressed people - feel better raised tantalizing (and troubling) questions about the future of mood-bending drugs. If Prozac gives you an up even when you're not down, why wouldn't you want to take it? Dr. Peter Kramer of Brown University asked that question in his best-selling 1993 book, Listening to Prozac. A drug that makes patients feel "better than well," he suggested, might give rise to a new era of "cosmetic psychopharmacology," in which reshaping your personality would be as easy as highlighting your hair...
...differ from that for an older child: the infant's version can actually be stronger since it is often administered in tiny amounts with a medicine dropper. "We've done studies here that show that 50% of the time, parents give the wrong dose" to a child, says Dr. Benard Dreyer, a professor of pediatrics at New York University. "We recommend parents don't use spoons...
Solving the Overkalix Mystery By early 2000, it seemed clear to Bygren that the feast and famine years in 19th century Norrbotten had caused some form of epigenetic change in the population. But he wasn't sure how this worked. Then he ran across an obscure 1996 paper by Dr. Marcus Pembrey, a prominent geneticist at University College London...
...1980s, Dr. Lars Olov Bygren, a preventive-health specialist who is now at the prestigious Karolinska Institute in Stockholm, began to wonder what long-term effects the feast and famine years might have had on children growing up in Norrbotten in the 19th century - and not just on them but on their kids and grandkids as well. So he drew a random sample of 99 individuals born in the Overkalix parish of Norrbotten in 1905 and used historical records to trace their parents and grandparents back to birth. By analyzing meticulous agricultural records, Bygren and two colleagues determined how much...
Exploring Epigenetic Potential How can we harness the power of epigenetics for good? In 2008 the National Institutes of Health (NIH) announced it would pour $190 million into a multilab, nationwide initiative to understand "how and when epigenetic processes control genes." Dr. Elias Zerhouni, who directed the NIH when it awarded the grant, said at the time - in a phrase slightly too dry for its import - that epigenetics had become "a central issue in biology." (See TIME's health and medicine covers...