Word: dr
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Dates: during 1990-1999
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...Women's Leadership Conference this past September where I met Dr. Oriol, she dispensed this advice: "At each intersection, you have to decide, `What do I want to do?' It might not look great, but that's okay. Don't be afraid to fail...
...supposed to be an innocent bystander responsible for "housekeeping" functions--like preventing ulcers. At the FDA meeting, proponents of the old-style pain killers suggested that that theory might be too simplistic. "The whole area of information about cox-1 and -2 is an evolving field," says Dr. Robert Palmer of SmithKline Beecham, which manufactures Relafen, a popular arthritis drug. "There's probably a whole lot of functions we don't know about...
Tell that to Dr. Philip Needham, father of the cox-2 inhibitor, who calls the white paper Palmer presented to the FDA panel "a predictable effort to protect their drug." If you want evidence that Celebrex works, he says, just ask the 13,000 arthritis patients who took part in its trial. "We're getting letters saying, 'Please don't take us off,'" Needham says. And the side effects? Pretty close to placebo levels...
...Dr. Steven Abramson, chairman of the FDA advisory panel, was impressed--and not at all surprised that the big drug companies were kicking up a fuss. "The cox-2 inhibitor will make it very difficult for them to compete," he says. Which could explain why Merck, Johnson & Johnson and Glaxo Wellcome are rushing to get their own versions into trial as fast as possible...
...iron supplements, including multivitamins, for at least a week beforehand. Even then, doctors don't always recognize the disorder. "I just had a patient in my office who was known to have a 100% iron-saturation level for years," but his physicians didn't do anything about it, says Dr. Geoffrey Block, director of the Hemochromatosis Clinic at the University of Pittsburgh Medical Center. "There's still a perception that if the iron levels aren't low, you don't need to worry...