Word: drastically
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...changes to the series, while seemingly drastic, represent a victory for Let’s Go in light of the St. Martin’s report issued last July, which recommended discontinuing the Let’s Go name and introducing an entirely new series of guides...
...explore new territory," said Carcelle. That meant Macdonald could break away from Givenchy traditions and do his own thing. Before the backdrop of a city skyline, Macdonald showed off couture versions of dresses from his popular ready-to-wear line. Shiny, strappy and asymmetrical, the frocks were a drastic switch from the Givenchy heritage he'd been mining - with little success - in previous seasons. With the departure of Saint Laurent, Valentino became the last couturier of his generation to design in his own name. The collection he showed clearly demonstrated why, despite his years, he's still the designer...
...more than 300 lbs., she was morbidly obese--more than 100 lbs. above her ideal body weight. After trying all sorts of diets that didn't work, the daughter of Beach Boy Brian Wilson and member of the now disbanded pop trio Wilson Phillips turned to a drastic last resort: gastric-bypass surgery. Doctors sewed up most of her stomach, reducing it to a tiny receptacle that holds several tablespoonfuls at best, and isolated much of her small intestine to reduce nutrient absorption. Result: filled to bursting after just a few swallows, she simply couldn...
...medicine at Harvard and an expert on obesity, "we'll be able to determine the complete wiring diagram for body-weight control." And once scientists understand the entire system, not just a few of its components, they may be ready to design drugs that will make obsolete the drastic surgery that Carnie Wilson underwent. --Reported by Heather Won Tesoriero/New York
...Drastic shifts in the national scene,” he wrote in his final presidential report at the end of the academic year, “have influenced immediately and profoundly the work of all our major institutions...