Word: dresden
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Dates: during 2000-2009
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What Simons calls the "Dresden model" has certainly worked for Cenix. The company's team of 26 scientists uses a technique called gene silencing, a procedure that selectively disables (or silences) individual genes. Once a specific gene--in a mouse, for example--has been silenced, researchers can determine that gene's function by the effect its silence has on the rest of the organism. It's kind of like isolating the role a single flute plays in a symphony by eliminating all the flutist's notes from the score. Pharmaceutical firms can use the information gleaned from gene silencing...
...wing of the Max Planck Institute, Germany's elite scientific research body. Echeverri didn't hesitate long, seeing the opportunity as a once-in-a-lifetime chance to prove that his theories actually worked. So when the new Max Planck Institute of Molecular Cell Biology and Genetics opened in Dresden in January 2001, Echeverri and his team moved in. Now, from its new labs, Cenix is working with drugmakers like Bayer AG to develop medicines based on an understanding of the roles of specific genes...
...creation of Cenix was not only a big switch for Canadian-born Echeverri, who loved the world of pure science. It also marks a shift for the venerable Max Planck Institute, which in Dresden is charting a new course to make Germany a major player in biotech research and development. Cenix is steaming in the right direction. "We're part of the wave of development that happened when the government and investment community made the push into biotech," says Echeverri, 35, his dark eyes darting to his cell phone to check text messages. "This year we're going to make...
...institute in Dresden--and others like it dotted around Germany--is starting to do things differently. Traditionally, German research universities are rigidly hierarchical. The head of the laboratory gets all the resources and, if there's a breakthrough, all the credit. The Dresden Max Planck Institute takes a more laissez-faire--in fact, a more American--approach. Its faculties are modeled after U.S. universities in which postdoctorate researchers have better access to funding, doing away with the top-down approach. The Dresden institute is also aggressively trying to attract researchers from outside Germany. "We are adapting the U.S. system...
...would never have come into being were it not for the extraordinary assistance and support from the MPG and in particular from its technology transfer agency, Garching Innovation. The combined start-up expertise of Ulrich Mahr (Garching Innovation), Torsten Mummenbrauer (Garching Innovation) and Ivan Baines (Max Planck Institute-CBG, Dresden), together with the forward-looking and innovative attitude within the MPG toward spinning out companies, are the factors that really contributed to the successful launch of Cenix. Christophe Echeverri CEO/CSO, Cenix BioScience GmbH Dresden, Germany...