Word: drugged
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Dates: during 1930-1939
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...Contrary to popular opinion, no vaccine, serum or drug has yet been devised that will give immunity, check the progress of the disease, or prevent final paralysis. Most polio workers now believe that the virus enters the body through the nose. Two years ago, Dr. Edwin William Schultz of Stanford University tried to protect 5,000 Toronto school children against the disease by flushing their noses with antiseptic zinc sulfate solution. The experiment, said Dr. Schultz in the new Bulletin, was a flat failure. But doctors still think nasal sprays a hopeful idea, hope some other chemical may prove more...
...friend of Dr. Ralph Robertson Mellon in Pittsburgh lay dying from blood poisoning caused by streptococcus. In despair, Dr. Mellon gave him a dose of prontosil (sulfanilamide), a German drug never before tried on human beings in the U. S. To his joy, the dying man made a rapid recovery. That was three years...
Chemists Russell J. Fosbinder and Lewis Aldro Walter of Maltbie Chemical Co. at Newark, N. J. last year created a new sulfanilamide product: sulfamethylthiazol. Biologists of Winthrop Chemical Co.'s Albany Laboratories fed the drug to mice infected with Staphylococcus germs, found it far more powerful, far less toxic than sulfapyridine. But even after hundreds of trials, no one dared experiment on human beings...
...last desperate measure, Dr. Carroll wired for a supply of sulfamethylthiazol. He gave his friend a small amount of the bland white crystals, both in capsules and injections. When the patient showed signs of improvement, Dr. Carroll continued feeding him from six to 14 grams of the drug every four hours for 16 days. In a few weeks the patient, said cautious Dr. Carroll, had "apparently recovered...
Since that time Dr. Carroll has used the drug with remarkable success on four other staphylococcic patients, including a baby. "No toxic symptoms or signs ascribable to this drug were seen," reported Dr. Carroll, "except for a slight nausea." About the future of the drug, which is not yet on the market, he hazarded no comment. Last week sulfamethylthiazol was tried on two Staphylococcus victims in a Midwest hospital, and on one in Manhattan, with hopeful results. But still restrained is the cautious enthusiasm of physicians, who cannot commit themselves on the drug until it has been tried on many...