Word: drugged
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Dates: during 1940-1949
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Penicillin was still making news last week. In Britain, its discoverer and chief developer, Professors Alexander Fleming and Howard W. Florey (TIME, May 15), were knighted by King George VI. Sir Howard reported progress toward chemical synthesis of the drug. In the U.S. the available supply for civilians was doubled: penicillin was shipped to 1,000 more hospitals, including some in Alaska, Hawaii, Puerto Rico, the Virgin Islands. But the biggest news was on the production front. In May, U.S. plants made 100 billion units of penicillin - one-third more than in April and just 250 times as much...
According to evidence in last week's Lancet, the new drug vivicillin (TIME, May 22) is not a good substitute for penicillin. The evidence (from a British military hospital): twelve cases of leg ulcers, carbuncles, boils, colitis, bacterial endocarditis, gonorrhea, septicemia which vivicillin failed to cure...
That was on September 15, 1941-two months before the Journal of the American Medical Association took up the subject-almost a year before even the New York Times mentioned it. After that other publications pricked up their ears, and scattered reports on the new drug began to appear. Meanwhile, by the end of 1943, TIME had printed no less than six separate stories on penicillin...
Winthrop Chemical Co. of Rensselaer, N.Y. was in trouble again last week.* The Pure Food and Drug Administration claimed that the company had distributed some 22,000 packages of improperly distilled water and 73,000 ampoules of dextrose solution (which is made with distilled water) containing pyrogens (fever-producing substances), "undissolved particles" and mold. Patients showed "unusual symptoms" when a Boston hospital used some of the dextrose in spinal anesthesia. According to an Assistant U.S. Attorney one patient died, but the doctors think he would have died anyway. Winthrop called in all the offending packages long...
...Samples of a captured Nazi drug, which is supposed to rival penicillin, were analyzed by British Army doctors, turned out to be marfanil, a sulfa drug. According to the New York Times, marfanil's "curative properties are second only to penicillin" and it is "no more toxic than sulfanilamide." The British Army has already tried...