Word: drugged
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...among the leading causes of health problems in the elderly. Each year, more than 300,000 Americans over age 65 suffer hip fractures, mostly due to falls, and 15% to 20% die within a year of their injury because of complications from infection or blood clots. While current drug treatments for osteoporosis slow down the destruction of existing bone, the new data suggest that denosumab may be more effective in promoting bone density. In addition, the studies show that denosumab did not cause the serious side effects - including cancer and the disintegration of bone in the jaw - that are associated...
...results of that study, called the Denosumab Hormone Ablation Bone Loss Trial (HALT), were especially welcomed by cancer doctors, since it was the first study to show that a drug can lower the risk of fractures in men with prostate cancer. So far, most trials of osteoporosis treatments have focused on postmenopausal women, who are at high risk of bone loss with the sudden drop in estrogen that occurs after menopause...
Currently only one anabolic agent, called teriparatide, is available. But because it causes the deposition of new bone, it has the potential to cause uncontrolled bone growth and osteosarcoma tumors; to avoid that, the drug can be given only for short periods of time - about two years. After the drug treatment stops, bone loss resumes...
...crazy alcoholic," says Wilder-Taylor, "but on the other hand, according to the news, her husband and family had no idea she had a drinking problem. Her husband says he's never seen her drunk. It would seem there are a lot of people out there with alcohol and drug problems not being addressed due to shame or other factors, and in some cases it leads to tragic results...
...team is also on the lookout for changes in the virus that might make it resistant to the antiviral drug Tamiflu, which has been shown to reduce the severity of the disease caused by many flu viruses. Tamiflu works by inhibiting the neuraminidase enzyme (that's the N in H1N1) and preventing it from doing its job of helping the virus replicate once inside a human cell. But certain amino-acid changes in the neuraminidase can render Tamiflu ineffective. This usually happens over time following extensive prescribing of the drug, but it can also occur spontaneously. In the winter...