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...natural compound used as an immunosuppressant in organ-transplant patients has been found to extend life in mice, according to a study published on July 8 in the journal Nature. Aging mice that were given the substance, rapamycin, lived significantly longer than mice that didn't get the drug: females that received rapamycin were 13% older at death and males 9% older...

Author: /time Magazine | Title: What Does Life-Extending Drug Mean for Humans? | 7/9/2009 | See Source »

Rapamycin's life-extending effect has been demonstrated by other researchers in past studies of worms, fruit flies and yeast; the drug appears to interfere with a similar cellular process in those species too. "I think this is a big leap from those invertebrate species to mammals," says Strong, who is also a senior research scientist for the Department of Veteran Affairs. "This gives us a good idea that perhaps it would work in humans...

Author: /time Magazine | Title: What Does Life-Extending Drug Mean for Humans? | 7/9/2009 | See Source »

...lead to heart disease. It's unclear whether these problems would counteract any longevity benefit that rapamycin might provide in humans. Says Strong, "I think more immediately, people are starting to look at [rapamycin] for age-related diseases like Alzheimer's disease, Parkinson's disease or kidney disease." The drug has also recently entered clinical trials as a human cancer treatment, while another study published last year showed that it may reverse mental retardation caused by the genetic disease tuberous sclerosis in mice. (See TIME's photo-essay "Access to Life...

Author: /time Magazine | Title: What Does Life-Extending Drug Mean for Humans? | 7/9/2009 | See Source »

...McCain's running mate, the day "the distractions," as she calls them, "ramped up." They ranged from the bizarre - a blogger's campaign to prove that Palin faked her last pregnancy (she didn't) - to the humiliating. The National Enquirer sent four reporters to Alaska, hoovering up gossip about drug use by her older children and long-ago marital infidelity. Despite rave reviews for her Republican National Convention speech, Palin soon became the target of late-night comics and snarky columnists. The obvious pleasure she took in her attacks on the Democrats made it hard to feel sorry...

Author: /time Magazine | Title: The Outsider: Where Is Sarah Palin Going Next? | 7/9/2009 | See Source »

Watch TIME's video about a drug war ambulance...

Author: /time Magazine | Title: Why Mexico's Voters Turned Back to the Future | 7/8/2009 | See Source »

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