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...between gay men is the leading mode of transmission, accounting for 37% of active cases. But the report also illustrates that incidence of infection through heterosexual sex and drug use remains high across all ethnic and age groups. Heterosexual sex is the leading mode of transmission among African Americans...

Author: /time Magazine | Title: HIV/AIDS: A Surging Epidemic in Washington, D.C. | 3/17/2009 | See Source »

...ever there was a safe recreational drug, modafinil seemed to be it. The greatest little pick-me-up since the cup of joe - or so its enthusiasts said - the antinarcolepsy medication has helped recreational and casual users stay peppy without the benefit of sleep. As for addiction? Not to worry. The drugs that hook you most powerfully do their work by mucking about with the pleasure-inducing brain chemical dopamine, but modafinil doesn't go there. "Modafinil," as Slate magazine claimed in a 2003 posting on the drug, "tiptoes around dopamine...

Author: /time Magazine | Title: Safety Concerns Raised Over Popular Wakefulness Drug | 3/17/2009 | See Source »

...This drug is not safe to use the way people are using it," says Dr. Nora Volkow, head of the National Institute on Drug Abuse and co-author of the new study. "Not safe at all." (See the most common hospital mishaps...

Author: /time Magazine | Title: Safety Concerns Raised Over Popular Wakefulness Drug | 3/17/2009 | See Source »

...spaces between cells, the longer its rewarding effect on the brain - and the likelier it is to lay down the roots of addiction. As Volkow and Fowler suspected, the PET scans of the men who had taken modafinil showed that dopamine transporters were indeed being blocked by the drug and overall levels were rising...

Author: /time Magazine | Title: Safety Concerns Raised Over Popular Wakefulness Drug | 3/17/2009 | See Source »

...Cocaine, amphetamines and methamphetamine all block dopamine transporters and leave dopamine in the extracellular areas," says Volkow. "Modafinil does the same." (Read "Can One Drug Cure Addiction to Another...

Author: /time Magazine | Title: Safety Concerns Raised Over Popular Wakefulness Drug | 3/17/2009 | See Source »

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