Word: drugged
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...British troops in Helmand are fighting with both hands tied behind their backs. They cannot go after the leadership of the Taliban - still led by the reclusive Mullah Omar - which operates openly in the Pakistani city of Quetta, just across the border. They also can't go after the drug trade that funds the insurgency, in part because some of the proceeds are also skimmed by the friends, officials and perhaps family members of the stupendously corrupt government of Afghan President Hamid Karzai. Helmand province is mostly desert, but it produces half the world's opium supply along a narrow...
...example, if a bacteria is treated with two drugs, A and B, and becomes resistant to drug A, then drug A is no longer an effective treatment. But if drug A suppresses some of the effect of drug B, then developing a resistance to drug A might allow drug B to become more potent, thus having an overall deleterious effect on the bacteria. In effect, Kishony said, “getting beat up by one is worse than getting beat up by both...
...Kishony and Chait had previously hypothesized that bacteria that became resistant to two drug that were known to suppress each other would not fare as well...
...Under Chait’s plan, researchers would spot various small molecules on petri dishes that contain mixtures of bacteria that are either sensitive or resistant to a particular drug. The sensitive and resistant bacteria would be labeled with different colors, such as green...
...compound that selects for resistance will generate a red ring, while a “selection-inverting” drug—those that temper the effects of another—will generate a green ring, indicating drug-sensitivity rather than resistance, Kishony said...