Word: drugged
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...idea that really does need to be rigorously evaluated," says Frank Vocci, director of the pharmacotherapy division at the National Institute on Drug Abuse (NIDA). "But right now there is more discussion than data...
...date, the research has been mixed but intriguing. The best-studied drugs so far are dexamphetamine, a form of amphetamine contained in the antihyperactivity drug Adderall, and modafinil, the wakefulness drug used to treat narcolepsy and shift-work sleep disorder. Most studies have been small and focused on safety rather than efficacy. Some have found no effect - but because of their size, it's difficult to determine whether that's meaningful...
...British study followed 60 stimulant addicts who were treated with dexamphetamine in a Cornwall clinic. Doctors tracked how well these patients fared compared with 120 heroin addicts being treated with methadone, and found an equivalent reduction in illicit drug use and drug injection. In both groups, about two-thirds of patients stopped injecting over 10 months...
...treatment was not initially studied more extensively. For one, high doses of amphetamines can cause brain damage, psychosis, heart attack and stroke. (High doses of opioids like methadone, in contrast, can also be dangerous, but once a patient develops a tolerance to them, even very high doses of the drugs are not toxic.) The consequences of high-dose use are important, since addicts in treatment often try at least once to use illegal drugs "on top" of their maintenance drug. So far, however, studies of dexamphetamine and similar drugs have not revealed major safety problems. Although a few patients have...
...several hours, cocaine and amphetamine feel different. As actor Robin Williams, an admitted ex-user, put it, cocaine makes you feel like a new man, and the first thing the new man wants is more cocaine. It produces excitement, not relaxation. And the concern is that a maintenance drug would have the same escalating effect...