Word: drugged
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...separate trial, an experimental drug called rember, developed by a Singapore-based company, also showed some promise in a safety study. Among 321 patients, rember appeared to stall advancement of the disease, degrading the protein tangles that build up in Alzheimer's brains. Potentially, a combination of drug therapies - designed to prevent both plaques and tangles - may prove effective in slowing the progression of the disease...
...future approaches won't stop with drug treatments. Petersen notes that researchers are also forging ahead with innovative screening tests to identify Alzheimer's patients sooner - before too much deterioration occurs in the brain. Better screens could also potentially identify patients by the specific type of brain buildup - plaques vs. tangles - that is causing them the most severe problems. That kind of triage early on could help doctors target the right patients with the most effective therapies...
...more discoveries are made, researchers hope they'll develop a better understanding of who is most at risk of Alzheimer's disease, how each patient's case is unique, and how best to treat specific patients with the drug and lifestyle changes that will be most effective for them. Taken together, these approaches could one day make the long goodbye of Alzheimer's a thing of the past...
...cause of ALS is that motor nerves die after exposure to a toxic compound released by other nerve cells in the spinal cord. The Harvard and Columbia groups are hoping to test that idea in the lab: if the cells in culture release the same agent, then finding drug compounds that block the damaging effects of the toxin could preserve neurons and hold off the paralyzing effects of the disease...
...which lies just on the other side of 8 Mile Road, Mayor Kwame Kilpatrick faces a long litany of legal and ethical woes stemming from his affair with a co-worker. Kilpatrick had to post a $7,500 bond to remain out of jail and take a court-ordered drug test. Republicans hope a weakened Democratic machine in Detroit will hamper Obama's effort in the fall. "Obama will have to go in himself and build his own machine," predicts GOP state-party chair Saul Anuzis. It's a fairly safe bet that the nation's first black presidential nominee...