Word: drugging
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...adolescents, ages 11 to 16, some of whom carried the short allele form of the gene 5-HTTLPR - a genetic condition found in about 40% of the general population and long associated with low self-control, binge drinking and substance use. Half of the participants were randomly enrolled in drug prevention programs. After five years, those participants with 5-HTTLPR who were enrolled in a prevention program were no more likely than their counterparts in the comparison group, without the gene, to have engaged in drinking, smoking marijuana, and sexual activity. Youths with the gene, who were in the comparison...
...drug, metoclopramide, is not approved by the U.S. Food and Drug Administration (FDA) for use in pregnant women, but it is dispensed widely in Europe and other places to treat morning sickness. In the new study, the largest one of maternal metoclopramide use to date, involving nearly 3,500 babies born between 1998 and 2007 in a region in southern Israel, the rate of congenital birth defects in babies born to mothers who used the anti-nausea drug was about the same as that in babies whose mothers had not (5.3% vs. 4.9%). What's more, the length of time...
...pervasiveness of pregnancy-related nausea, there is still no easy treatment, since most expecting mothers and their doctors aren't keen on exposing a still developing fetus to medications. Now, researchers from Israel and Canada report in the New England Journal of Medicine that a commonly prescribed heartburn drug, which also has anti-nausea properties, may be used in pregnant women without causing harm to babies. (See safety issues about taking pills during pregnancy...
Until now, there have been only about half a dozen studies looking at metoclopramide as a treatment for morning sickness. Even taken together, these studies include only about 500 babies. Because of the paucity of data, most doctors have prescribed the drug for nausea infrequently and only as a last resort - for instance, in cases where nausea and vomiting are so severe that a woman cannot function. Most mothers-to-be in the U.S. are given antihistamines instead, which help calm queasiness with few lasting effects on the fetus; the only downside for moms is side effects like drowsiness. (Read...
...before that can happen, he warns, more studies need to be done on how well metoclopramide actually controls nausea. At the moment, the drug, which calms digestive activity by slowing the contraction of intestinal muscles, is approved by the FDA only for the treatment of heartburn and other intestinal disorders. The drug's mechanism is believed to combat nausea by relieving the spasms that prompt queasiness. "What happens when people vomit or feel nauseous is that everything is stopped up," says Koren. "Metoclopramide helps move things forward and does not cause sedation like antihistamines...