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...caveat” of using warfarin to inhibit tuberculosis growth is the need to apply very high concentration of the drug to produce desired results—and high dosages of the drug may cause a patient to bleed to death, according to graduate student and lead researcher Rachel Dutton...
Beckwith’s team is currently developing screening assays for various anticoagulants and antibiotics to test whether they inhibit VKOR’s enzymatic activity. Dutton said they hope to “find other small molecules that would be stronger inhibitors that could potentially serve as starting points for new TB antibiotics...
After a simple incident of crowd interference in a baseball game, Ogden Marsh is stripped of any peace or tranquility. When the town drunk stumbles onto the baseball field carrying his shotgun, Sherriff David Dutton, played by the first-rate Timothy Olyphant (known best as the porn producer in “The Girl Next Door” and the cyber-terrorist in “Live Free or Die Hard”) confronts and eventually guns down the inexplicably aggressive drunk, as the entire town attentively stares through the baseball diamond’s chain link fence. The scene...
Ogden Marsh, Iowa, is one of those remote towns even the flyovers don't fly over. But for decades its citizens' decency has matched the town's anonymity. Dr. Judy Dutton (Radha Mitchell) takes care of the births and the ordinary illnesses; her husband David (Timothy Olyphant), the local Sheriff, keeps the peace with the aid of his Deputy, Russell Clank (Joe Anderson). Nice town, y'know what I mean? Until that day during a school baseball game when Rory Hamill strode out of center field carrying a shotgun he wouldn't put down, and David had to shoot...
...Prince Charming to sweep them off their feet? Is it time to stop pining for Mr. Right and start considering Mr. All Right? Journalist and NPR commentator Lori Gottlieb raises these questions and others in her new book, Marry Him: The Case for Settling for Mr. Good Enough (Dutton). TIME senior reporter Andrea Sachs discussed the dating scene with Gottlieb. (See TIME's Pictures of the Week...