Word: duve
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...Last week Sweden's Karolinska Institute! honored the three men whose work has provided scientists with just such knowledge. The $125,000 Nobel Prize in Physiology or Medicine went to Dr. Albert Claude, 75, of the Free University of Brussels' Institut Jules Bordet; Dr. Christian R. de Duve, 57, of New York's Rockefeller University and Belgium's University of Louvain; and Dr. George E. Palade, 61, of Yale University's School of Medicine...
...triple award was appropriate, for both De Duve and Palade based their own work on the pioneering studies of Claude. All three men did the major and most significant parts of their work at Rockefeller University, which has produced twelve other Nobel laureates...
Aggressive Enzymes. De Duve, a Belgian citizen, in 1962 joined Rockefeller U., where he continued to refine the fractionalization techniques developed by Claude. His studies led to the discovery of lysosomes, aggressive enzymes that work as a sort of digestive system, breaking down the substances ingested by the cell-and in some diseases or disorders, destroying the cell itself...
KIRKLAND HOUSE DINING HALL, Shorts: de Duve, Why Man Creates, Un Chien Andalou, the Critic, Easy Street, To Parsifal, Jan. 18,19, at 8 and 10:15, $1 LEVERETT HOUSE DINING HALL, Woody Allen in Take The Money...
Electron microscopists have since photographed lysosomes, and Dr. de Duve, now at Rockefeller University, has figured out some of the ways they work (see diagram). In a typical case, a foreign particle (it may be a virus, a bacterium or a chemical) reaches the side of a cell and is sucked in, sealed off by a piece of the cell's own membrane. Standing by inside the cell is a lysosome, packed with enzymes. Lysosome and invader, now packaged in a phagosome, are drawn together and fuse. In the resulting sac, called a vacuole, the foreign substance is digested...