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Then in July, at an international AIDS conference in Vancouver, a virologist named David Ho reported on a most promising experiment. By administering the protease-inhibitor cocktails to patients in the earliest stages of infection, his team seems to have come tantalizingly close to eliminating the virus from the blood and other body tissues. Mathematical models suggest that patients caught early enough might be virus-free within two or three years...

Author: /time Magazine | Title: TURNING THE TIDE | 12/30/1996 | See Source »

...this time, most researchers agreed that people in the later stages of AIDS had large quantities of HIV in their blood. But the PCR test showed that millions of viral particles were coursing through Ho's patients' blood in the earliest weeks of infection as well--as many as could be found in someone with a full-fledged case of AIDS. Within a few weeks, the viral load plunged to low and in some cases undetectable levels. The patients recovered and seemed healthy...

Author: /time Magazine | Title: DR. DAVID HO: THE DISEASE DETECTIVE | 12/30/1996 | See Source »

...find out, Ho and one of his team, Dr. Martin Markowitz, recruited two dozen men in the earliest stages of infection and placed them on combination therapy. All the men appeared healthy before treatment. For them, ironically, the first signs of illness have been the side effects of the drugs they are taking, not the virus. Three have dropped out because they couldn't take the nausea and cramping...

Author: /time Magazine | Title: DR. DAVID HO: THE DISEASE DETECTIVE | 12/30/1996 | See Source »

Many of the couple's most famous discoveries were hers. One of the earliest occurred in October 1948, when Mary caught the glint of a tooth during an expedition to Lake Victoria's fossil-rich Rusinga Island. It was part of the jaw and skull fragments of a creature called Proconsul africanus, then widely thought to be a human ancestor (though now considered more closely related to the apes). The discovery made them so "exhilarated and also utterly content with each other," Mary wrote in her 1984 biography, Disclosing the Past, "that we cast aside care..." She gave birth...

Author: /time Magazine | Title: MARY NICOL LEAKEY: 1913-1996: FIRST LADY OF FOSSILS | 12/23/1996 | See Source »

...more complete guide to the world's art exists; this is especially true of the range of cultures outside the West, both old and modern, such as Aboriginal Australia, Oceania or ancient Egypt. The discussion of Japanese art, from its earliest beginnings to the 20th century, extends to 431 pages, and it is a brilliant feat of compression even at that length, without a wasted word. Moreover, every major subject has multiple entry points: individual artists, schools, national origin, techniques and so on. There's no art publication in existence that gives the reader such richness of detail and coherence...

Author: /time Magazine | Title: BOOKS: TOWERING VENTURE | 11/4/1996 | See Source »

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