Word: effect
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Dates: during 2000-2009
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...Angeles, and a host of other institutions, data suggest that a new chemical compound may sidestep the problem of resistance. When used to treat mouse tumors that were derived from drug-resistant prostate-cancer cells, the compound led to dramatic shrinkage, which has researchers hoping for a similar effect in humans. "The compounds are working extremely well in our models," says Sawyers. "We think this might be able to deal with the resistance question." (Read "Prostate Exams: When Are They Necessary...
...That trial - needed before MDV3100 can be approved for use in humans - will take several years. In the meantime, there are still questions to be explored, including why the drug had little effect in eight of the subjects in the early clinical trial. Sawyers' team is working on an answer. It's possible that the drug may have to be given in larger doses to some patients or that some prostate cancers may mutate to the point where antiandrogen drugs are simply ineffective. "There could be changes that are preventing the drug from binding," he says...
...Crocker wants to recruit at least one experienced player to minimize the effect of losing Nick. With the team’s growth this past year, several interscholastic players from all over the world—including one from Singapore that Crocker especially has his eyes on—have expressed interest in the club. If he were to have a say in the selection between two very similar applicants—one with polo experience, the other without—it could yield unimaginable gains for the Harvard team, Crocker says...
...Pausing for effect, he added, "I know, because I am one of them." Applause broke out in the chambers...
...second day, Obama used the symbolism of Istanbul - the former seat of both the Byzantine and Ottoman empires and a city that bridges Europe and Asia - to full effect. He toured the historic Blue Mosque and Hagia Sophia (a church converted into a mosque and now a museum), met with religious leaders of all faiths and held a town-hall meeting with 100 university students. He also reiterated his commitment to a two-state solution in the Middle East, despite the potential roadblocks posed by the new Israeli government under Benjamin Netanyahu. "Peace in the Middle East is possible...