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...team screened nearly 3,700 compounds—over a third of all FDA-approved drugs—to determine those that could effect a shift from respiration to glycolysis. In the process, researchers discovered that Meclizine can inhibit mitochondrial respiration by shifting cellular metabolism—a promising find for the treatment of heart attacks and strokes...

Author: By Katherine M. Savarese, CONTRIBUTING WRITER | Title: Common Drug May Revolutionize Treatment of Strokes and Heart Attacks | 2/19/2010 | See Source »

...kids who aren’t getting anything out of that grade.” However, there is nothing intrinsic to the 12th grade that breeds a decline in intellectual curiosity among students; early graduates might just as easily experience an equivalent “junioritis” effect. To address the underlying issue here, the current educational system would benefit from fundamental reform aimed at keeping school meaningful to students throughout their high school careers...

Author: By The Crimson Staff | Title: Stay in School | 2/18/2010 | See Source »

That's the envelope-expansion effect, where - following the trail cleared by Gates - subordinates know they too can be resolute. "These kinds of things do have a cumulative effect," says Eugene Fidell, president of the National Institute of Military Justice. "You get the sense that Secretary Gates has his hand on the tiller." When the boss makes clear what he expects - and shows there are penalties for falling short - even a bureaucracy as massive as the U.S. military can respond...

Author: /time Magazine | Title: The Military's New Surge in Accountability | 2/17/2010 | See Source »

BANANAS BISTRO Hidden high in the tropical rainforest, this charmingly boho restaurant, tel: (1-869) 469 1891, features a wraparound veranda and art-filled interior. The menu mixes Spanish, North African and even Thai flavors with Caribbean ingredients to delicious effect. Don't miss the spiced lobster cakes...

Author: /time Magazine | Title: Spoiled for Choice on Nevis | 2/17/2010 | See Source »

...then, the population has plummeted, from at least 5,000 to just 52 people now lumped together in a sprawl of cottages on one island. For most of those left, especially children, specific tribal tongues have given way to a pidgin Andamani dialect of Hindi. Boa Sr was in effect their last link to the olden days. "It's the end of thousands upon thousands of years of history," says Miriam Ross, spokeswoman for Survival International, a London-based NGO that defends the rights of tribal peoples. "A whole way of looking at the world is finished, and there...

Author: /time Magazine | Title: Off the Coast of India, Another Language Dies | 2/17/2010 | See Source »

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