Word: eggan
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...news was huge - but it was also a lie. In 2006, Hwang admitted he had falsified his results. (Melton's colleague at HSCI, Kevin Eggan, finally created embryonic stem cells from patients in 2008.) Although Hwang became a pariah, he had the right idea. Melton and others had been trying to do just what the Korean scientist claimed to have done - grow a new population of a patient's own cells. The key to the process is a supply of fresh, good-quality human eggs, which incubate skin cells taken from a patient. Building up such a stockpile, however, proved...
...some ways from their embryonic counterparts. In mice, embryonic stem cells can generate a new mouse clone; iPS cells from the animals have so far stopped short of the same feat, aborting in midgestation, suggesting that some development cues may be missing. "It certainly makes me cautious," says Eggan...
...week’s story about the successful transplantation of a windpipe grown from stem cells. But while transplantation is “a very exciting application of stem cells,” it is not a solution for many diseases, as stem cell and regenerative biology professor Kevin Eggan said in a talk last night, titled “Using Stem Cells and Reprogramming to Model Neural Degeneration.” For example, he said it is difficult to imagine growing a new forebrain in the case of Alzheimer’s Disease, which is effectively what would need...
...spent roughly $100,000 on advertising," Eggan said. "We've only had one woman follow through and go through the considerable effort of donating oocytes [egg cells] for research. I would characterize the number of oocytes she donated as a handful. And the results we had from those very few initial experiments were encouraging, but there's no sign of additional donors in sight...
...addition, the stem cells are specific to only a certain type of the disease, which afflicts less than five percent of sufferers, Eggan said. But the study authors said research on this less-common variant could have broader applications, if, as they hope, the disease mechanism is similar for most or all types of Lou Gehrig's disease despite different initial triggers in the vast majority of ALS patients...