Word: embryos
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Dates: during 1990-1999
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...journal Science reports that researchers at Harvard Medical School have successfully harvested basic chicken legs in chick embryos -- complete with leg-like muscles, and clawed implements -- by transferring a leg gene called Pitx1 into the area of the embryo where the wings usually sprout. Learning about the role of genes in limb formation, they believe, will lead to a greater understanding of limb development in humans and greater knowledge of Holt-Oram syndrome, a condition that produces truncated forearms...
...scientists chose to work with Pitxl because it is present during the early stages of the chicken embryo's development. Logan and Tabin believe that Pitxl activates other genes responsible for limb-specific development...
...that Pitxl has been identified as a key regulator of limb formation, Logan said he wants to further examine the effects of this gene on embryo development...
...interested in understanding the morphogenesis of the entire embryo," Tabin said, referring to the embryo's developmental stages. "In terms of Pitxl, I want to understand more what it does in limb patterning...
Although the study does not have any direct implications for the treatment of humans, Logan said the experiments would help scientists gain a better understanding of developmental disorders in the human embryo...