Word: enbrel
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...Soumerai and Law focused on three drugs—Enbrel, Nasonex, and Zelnorm—all of which had been on the market for at least one year before the advertisements started popping up on television. The researchers then analyzed prescription statistics of these drugs from a five-year period using information from IMS Health Canada, a health information company that compiles data from about 2,700 Canadian pharmacies...
...Seed himself has become a tech transfer success story. Research in his lab led to the development of Enbrel, a rheumatoid arthritis drug. His hospital, Mass. General, has sold rights to the discovery and earned $400 million for itself...
Over the past few years, powerful drugs like Remicade and Enbrel, which target specific inflammatory cytokines, have worked wonders against rheumatoid arthritis and other autoimmune disorders. But as often happens in medicine, the drugs have also created some problems. Patients who take Remicade, for example, are slightly more likely to develop tuberculosis; the same inflammatory cytokines that attacked their joints, it seems, also protected them against...
...Cohen, "if we treat early and we treat aggressively." Today the most effective treatments for rheumatoid arthritis are combination therapies. Methotrexate, a cancer drug which has been used to treat RA for 30 years, is augmented by other drugs, including the recently developed but costly "biologics" such as etanercept (Enbrel), infliximab (Remicade) and anakinra (Kineret). These are genetically engineered versions of naturally occurring molecules that bind or block the activity of cytokines. Also in very early development are drugs designed to reduce the formation of the blood vessels that feed the tumor-like growth of the synovium...
...Deutsche Banc Alex. Brown concurs: she says estimates for Bristol's earnings are too low--she's penciling in 13% or 14% annually over the next three years. And now that the fen-phen fiasco is behind American Home, she says, the company can concentrate on drugs like Enbrel for rheumatoid arthritis...