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...replaces bone tissue throughout life, the destruction eventually begins to overtake the construction, and the result in older age is a patchier, weaker type of bone that is more prone to breaking. While bisphosphonates block the activity of bone-destroying cells, denosumab prevents new ones from forming altogether. The end result is a tipping of the bone balance away from bone destruction and toward bone formation. Early studies in mice at Amgen, the company that developed denosumab, showed that animals given higher amounts of this compound developed thicker, more robust bone...

Author: /time Magazine | Title: Experimental Drug Helps Treat Osteoporosis | 8/11/2009 | See Source »

...embracing art because, as the economy gives us reason to be pessimistic, art gives us good reason to hope. But more likely, this particular brand of hope has clearly been present in Washington for a long time. Instead of stemming from a campaign slogan, art is the logical end product of a country that values free expression...

Author: By Nathaniel S. Rakich | Title: It's a Free Country! | 8/11/2009 | See Source »

...have to admit a certain amount of moral struggle that I faced as a faculty member of an institution whose students condescendingly referred to me as a “local” while I grew up in neighboring North Andover. Now, at the end of the summer, I have seen the other side of the campus’ New England brick and, I hope, gained a great lesson in moral growth...

Author: By Jeffrey J. Phaneuf | Title: We Who Never Set a Squadron in the Field | 8/11/2009 | See Source »

...hate the fact that when a man does something idiotic and criminal resulting in the death of a child, that isn't held out as some Searing Indictment of Modern American Fathers, but a woman's colossal, tragic screw-up somehow does end up reflecting on all her fellow mothers," says Carole Morrell, author of the popular parenting blog DrunkenHousewife.com. "In this particular instance, I'm sure this will confirm the belief held by many that a mother should never drink around her children, ever...

Author: /time Magazine | Title: Moms Who Drink: No Joking After the Schuler Tragedy | 8/11/2009 | See Source »

...record having said this is unlike other crises, and it's the most serious crisis we've faced and it will have long-term repercussions. It's the end of an era, and there will have to be major adjustments. Those who expect that we will return to business as usual don't understand what's happening. See TIME's Pictures of the Week...

Author: /time Magazine | Title: Billionaire George Soros' Private Stimulus Plan | 8/11/2009 | See Source »

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