Word: endocrinologist
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...leptin's discovery was big news to biologists, particularly after Friedman administered it to the obese mice and saw their weight drop by a dramatic 30% within as little as two weeks. A next, obvious step was to look for humans with the same defective gene. In Britain, endocrinologist Stephen O'Rahilly of the University of Cambridge did find a pair of leptin-deficient children, one of whom at age 9 weighed a staggering 208 lbs. After modest leptin treatments were begun, both children began dropping weight at a steady rate that sometimes exceeded 4 lbs. a month...
...self-esteem for youths, especially preadolescent girls. And researchers say the price tag for medical care for obesity-related diseases, about $100 billion a year, may get steeper. "You are more likely to be an obese adult if you're obese as a kid," says David Ludwig, a pediatric endocrinologist at Children's Hospital in Boston. "And if you're a sedentary child, you're more likely to be a sedentary adult...
...When endocrinologist David Ludwig, director of the Optimal Weight for Life (OWL) Clinic at Boston's Children's Hospital, first met Bernadette and Wayne in May last year, he found that Wayne was 25 lbs. over his ideal body weight. Then came the shocker: on the nape of Wayne's neck was a dark, velvety area, an abnormality neither Bernadette nor Wayne's grandparents, whom he saw daily, had noticed. The skin condition indicated risk for Type 2 diabetes. While Wayne didn't yet have the disease, advised Ludwig, he would need to be monitored. Wayne was so stunned...
...breast development (as opposed to menstruation) has dropped or over what period. That's because a key piece of research that helped set the standard age at 11 was a small study in the 1960s of white girls raised in English orphanages. But Dr. John Dallas, a pediatric endocrinologist with the University of Texas Medical Branch in Galveston, points out that the British girls may have been poorly nourished--a factor known to delay puberty. African- American girls were studied even less rigorously. "For all we know," says Dallas, "African-American girls could have been earlier developers for a long...
...Paul Kaplowitz, a pediatric endocrinologist with the Virginia Commonwealth University School of Medicine in Richmond, Va., explains, "We've known for a long time that very overweight girls tend to mature earlier, and very thin girls, such as anorexics, tend to mature later than normal. We think mildly overweight girls may be maturing early as well." Kaplowitz emphasizes that the correlation is merely statistical; not every girl with a little extra baby fat will develop breasts early...