Word: enterings
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...substantial portion of drugs taken orally, in pill or liquid form, is lost to digestive processes and removed by the liver, and what remains can irritate the intestinal tract. Enter transdermal patches. First designed to treat motion sickness, they slowly deliver drugs through the skin from a reservoir within the patch, and are being used increasingly to treat hypertension, angina and other disorders. So far, the patches are limited to carrying small-molecule drugs that can diffuse through the skin. But several teams are experimenting with electrical or ultrasonic devices that can also push larger-molecule drugs through the skin...
...classic rock or oldies) and asked to love everything in it? On the other hand, it must also be at least a year since I've had the thrill of discovering a toe-tapping tune from an unknown artist completely by accident. This is what happens when you enter the world of Napster and MP3s. You tend to play it safe, downloading artists you know or songs you remember from childhood. It eventually gets stale...
Last year one of these highly refined derivatives became the first so-called secretase inhibitor to enter clinical trials with Alzheimer's patients, and others seem sure to follow. In fact, not just Bristol-Myers Squibb but also Amgen, Elan Pharmaceuticals, Eli Lilly, Merck and SmithKline Beecham are racing to develop similar compounds. The reason? Over the past five years, an explosion of insights into the genetics of Alzheimer's has bolstered confidence that gamma secretase and a related enzyme called beta secretase are not innocent bystanders but rather are intimately involved in the disease process...
McCormick's story is one of hundreds of similar tales coming out of laboratories and cancer wards around the world, as treatments that were little more than half-baked ideas a decade ago now enter the final stages of testing. Of some 350 new compounds and molecules being tested on cancer patients, more than half are based on innovative, sometimes bizarre-sounding ways of homing in on tumors. Hundreds more are in earlier stages of development, putting clinicians and drug companies in the novel position of having more promising cancer treatments waiting to be evaluated than they can possibly handle...
SCOUT MASTER That stack of business cards waiting to be entered into your address book is not getting any smaller--and you're not getting any younger. Scout, a free service from Ants.com could be your ticket out of data-entry hell. Sign up, and when you enter another Scout member's e-mail address into your Outlook database, her contact information (or whatever part of it she's willing to share) is automatically filled in. Scout will update contact information continuously--no more mass e-mails for address changes. The software is still in its early phases, though...