Word: ergot
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When such simple remedies as aspirin fail, the standard treatment has been shots of ergotamine tartrate (Gynergen). But Gynergen, derived from ergot, a drug used to stimulate uterine contractions in childbirth, is almost a disease in itself. It slows the pulse, raises blood pressure, occasionally causes gangrene, may cause vomiting, pains in the legs, uterine cramps and suppression of menses...
...Proceedings of the Staff Meetings of the Mayo Clinic, Dr. Bayard T. Horton & coworkers point a way out of this miserable dilemma. Having tried it on 120 patients over three and a half years, they announced that a new derivative of ergot, dihydroergotamine, has all the virtues of Gynergen and almost none of its vices...
...Ergot, a fungus which grows in rye kernels, contains a score of medicinal factors. It is used mostly to start contractions of the uterus at childbirth. The fungus is difficult to separate from rye husks, is expensive to produce. Most of it came from Europe. About 20,000 Ib. were produced in the Middle West last year...
...medical profession is concerned, that shrewd controversy raised by Howard W. Ambruster, Manhattan importer of crude ergot, and Dr. Henry Hurd Rusby, Columbia University pharmacologist, as to the purity of ergot used obstetrically in the U. S., is ended. The American Medical Association last week published a 10,000-word review of the entire dispute from its beginning in 1927 (when Mr. Ambruster secured a "corner" on Spanish ergot) through the Senate investigation of the Food, Drug & Insecticide Administration last summer (TIME, July 14 et ante).* In passing the report revived its old comment on Dr. Rusby: "His experience...
...also flayed Dr. Edward Joseph Ill, "personal friend and neighbor of Dr. Rusby for a great many years," "honest and well meaning" Newark, N. J., obstetrician. Dr. Ill, in the name of the Association of Obstetricians, Gynecologists and Abdominal Surgeons, supported the Ambruster-Rusby denunciations of commercial ergot preparations...