Word: escherichia
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...first stage of the experiment, NIH'S Malcolm Martin and Wallace Rowe will splice DNA from the polyoma virus (which causes tumors in mice but not in humans) into a specially engineered strain of the common bacteria Escherichia coli. The bacteria will be fed to or injected into mice and hamsters, which will then be examined to determine 1) if the bacteria multiply into progeny that also contain the viral DNA, and 2) if the bacteria-carried viral DNA can cause tumors in the animals...
...important step in this direction had already been taken last spring when scientists at the University of California in San Francisco succeeded in transplanting a rat insulin gene into the DNA of a laboratory strain of the bacterium Escherichia coli. The bug then multiplied into countless duplicate bacteria, each containing the insulin gene, but incapable of producing insulin. In the work announced last week, Microbiologist Herbert Boyer of the University of California, San Francisco, along with Biochemist Arthur Riggs of the City of Hope Medical Center near Los Angeles and Physiologist Wylie Vale of the Salk Institute in San Diego...
...basic molecule of life, might accidentally lead to the creation of new, uncontrollable strains of disease-carrying bacteria. Now most experts have decided they greatly overstated the dangers. But many laymen have remained frightened ever since research at Harvard designed to create new combinations of DNA in the bacterium Escherichia coli K12, or E. coli for short, stirred passionate debate last year (TIME cover, April 18). Last week, after long hearings, Congress was scheduled to act on two bills seeking to control such research. The rush to adjourn forced a postponement of action until after the summer recess...
...this reason and because of the increasing demand for the hormone, which the body needs to turn sugar into energy, drug companies seeking alternative sources have pinned some of their hopes on recombinant DNA technology. By inserting the human insulin gene into the DNA of the common intestinal bacterium Escherichia coli, they could, in theory, endow the bug with the capacity to make human insulin...
...tiny parcel of protoplasm has now become the center of a stormy controversy that has divided the scientific community, stirred fears-often farfetched-about tampering with nature, and raised the prospect of unprecedented federal and local controls on basic scientific research. Last week the bacterium known to scientists as Escherichia coli* (E. coli, for short) even became a preoccupation at the highest levels of government...