Word: estradiol
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Dates: during 1980-1989
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...main female sex hormones, after menopause; a third of them were also on progestin, an artificial form of the hormone progesterone. The researchers compared these women with others who had not taken hormones. The results: after nine years the women who took a kind of estrogen called estradiol had about twice the breast-cancer rate of those who were not on replacement therapy. The women on estrogen and progestin had a higher rate -- about four times as many cases of breast cancer after they used the combination for six or more years. Medical experts point out that parts of this...
...University of California, San Diego, argues that the "benefits of estrogen seem strongly established. In my opinion, the data are not conclusive enough to warrant any immediate change in the way we approach hormone replacement." Dr. I. Craig Henderson of the Dana-Farber Cancer Institute in Boston notes that estradiol, the estrogen implicated in the Swedish report, is not the same as the estrogens most commonly used in the U.S. "While women should not conclude yet that they are totally without risk," he says, "it is highly likely that the estrogen American women use may be safer for a longer...