Word: estrogen
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Dates: during 1980-1989
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...teams. The research, which should explain why only some exercising women experience the menstrual dysfunction that can lead to a reduced cancer risk, will include studies on the amount and location of fat present in the bodies of participants, as well as body fat's effect on the way estrogen is metabolized...
Snow, who also works at the Center for Population Studies, has researched estrogen metabolism in female athletes, basing most of her conclusions on a study of 10 "elite oarswomen" and the way their bodies process the female hormone involved in developing secondary sex characteristics...
...found that those athletes with menstrual dysfunction while in high-intensity athletic training metabolized a greater fraction of their estrogen to "non-potent" forms, to which the reproductive organs will not respond. The increase in non-potent estrogen production also means that there is less normal hormone circulating in the blood, and this may lead to a lower risk of estrogen-dependent tumor development, such as breast cancer, Snow says...
However, Snow, a former member of the national lightweight rowing team, found that not all women who exercise metabolize their estrogen in this way. Those women who do have the metabolic abnormality also have menstrual dysfunctions, are leaner and do not ovulate...
...current research project centers around four sets of tests under the direction of a pair of physicians at the Brigham and Women's Hospital and the Massachusetts General Hospital (MGH). Three of the procedures measure body fat, and the other traces estrogen metabolism in the body...