Word: estrogen
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...tranquilizer Valium. FDA Commissioner Jere Goyan, a pharmacist, supports this truth-in-prescription experiment, but acknowledges that PPIs may have surprising side effects. He cites the case of a friend's wife who underwent a hysterectomy, or removal of the uterus. Later she was given a prescription for estrogen, for which the FDA has required PPIs since 1977. After reading the leaflet, she immediately wanted to stop taking the hormone. Her reason: she was afraid of developing cancer of the uterus...
Some 2 million pregnant women had taken DES (diethylstilbestrol) to help prevent miscarriage before the Food and Drug Administration alerted physicians to its dangers in 1971. Doctors suspected that the estrogen drug was causing vaginal and cervical cancer in daughters born to those women, and more recently have also implicated it in genital abnormalities and infertility in sons. Now there is more unsettling news for DES daughters. When they reach childbearing age, they appear to be more vulnerable than others to miscarriage-as well as to stillbirth, premature birth and ectopic pregnancy (in which the fetus grows outside the uterus...
...than 100,000 sniff tests to determine changes in the ability of volunteers to detect a chemical called furfural, a scent found in cloves and cinnamon. One clear result: women have the greatest ability to detect the odor midway in their menstrual cycle, presumably because of a correlation between estrogen in the body and sensitivity at the nose...
...month study, the doctors monitored 296 women up to age 76 who had undergone mastectomies. From tissue samples physicians found that three-quarters of the women had estrogen-linked tumors. These patients, as well as the others whose cancers were not connected with the hormone, were divided into three treatment groups: one was given a combination of drugs known as CMF; another CMF and tamoxifen; and the third CMF, tamoxifen and BCG (which is designed to bolster the immune system...
...estrogen group, the relapse rate was 40% in those treated with CMF alone. But, remarkably, among women who had also been given tamoxifen, cancer reappeared in only about 10% of the cases...