Word: estrogen
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...other measures now under consideration could reduce the harmful effects still further. British research, cited repeatedly at Nelson's hearings, suggests that the risk of clotting is somewhat greater with the sequential pills. It is also directly related to the amount of estrogen in either type of Pill, and is markedly increased if the estrogen component is more than 50 micrograms (less than two millionths of an ounce). Britain has already officially discouraged the dispensing of pills with any higher estrogen content. By this reasoning, women in the U.S. would find themselves limited to seven...
...types are approved for general prescription: 1) 21 daily combination pills containing synthetic equivalents of the hormones progesterone and estrogen, with the latter in a microscopic dose; 2) sequential pills, which provide tablets of an estrogen alone for 14 to 16 days, followed by five to seven combination tablets. A third variety, the "one-everyday" pill of progestin (progesterone equivalent) only, is being tested but is not yet licensed for U.S. prescription...
...birds, DDT kills off the young by interfering with the female's egg-laying process. Though the exact chemistry is still obscure, the pesticide apparently sends the mother bird's liver into a frenzy of enzyme production. The excess enzymes break down such steroids as estrogen that are essential to the manufacture of calcium. Lacking adequate calcium, the bird's eggs emerge thin-shelled and flaky, offering scant protection for the embryo. In at least one instance, reports the National Audubon Society, which has just joined the public crusade against DDT, a bald-eagle egg was found...
...METABOLISM. Estrogens, but not progesterone, have long been known to influence the metabolism of fats-to the point where they have been given to men in the hope of lowering their blood-cholesterol levels and protecting them against heart attacks. In fact, says the University of Miami's Dr. William N. Spellacy, their effect on cholesterol is still debatable; they seem to increase the proportion of big, "flabby" fat molecules circulating in the blood. The most consistent finding, said Spellacy, is that increased estrogen levels cause increased blood levels of triglycerides, the complex, fat-containing molecules involved in atherosclerosis...
...blood vessel bursts. Strokes are uncommon among women under 40, but several neurologists say they have seen as many as ten cases in a year among women on the Pill, where they used to see only one or two before the Pill. Both the increased blood pressure and the estrogen's effect on the clotting mechanism may be responsible. There are a few authenticated cases of severely impaired vision, even to the extent of blindness, as the result of clotting in the minute retinal arteries...