Word: estrogen
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Manhattan Obstetrician Raphael Kurzrok believes that a large number of miscarriages are caused by "genital hypoplasia" (malformation plus deficient hormone activity). His analysis: in some women, because of insufficient output of estrogen (a female hormone) during pregnancy, expansion of the uterus fails to keep pace with growth of the fetus. Rupture of the membrane and miscarriage result...
...genital hypoplasia sufferers who desperately want to become mothers, Dr. Kurzrok holds out new hope: hormone therapy. In the current New York State Journal of Medicine he reports on the treatment of 42 women with previous histories of repeated miscarriages. After a daily dose of estrogen throughout the months of pregnancy, 39 gave birth to normal children; two had miscarriages for other reasons than genital hypoplasia, one for an undetermined cause...
...yellow mass in the ovary) and in the placenta of various animals. But he had failed to determine its chemical composition. And his theory seemed to be knocked into a cocked hat when several European investigators succeeded in relaxing animals with injections of the well-known ovarian hormones, estrogen and progesterone...
...Actor. Last week, however, Dr. Hisaw and his assistants reported in Endocrinology that the relaxing material could not possibly be estrogen or progesterone, that it must indeed be a new hormone. The proof was partly chemical: they produced a concentrated ovarian extract from which estrogen and progesterone (which are soluble in alcohol) had been removed; the extract nonetheless had a strong relaxing effect. But the most significant evidence was a contrast in speed between relaxin and progesterone. Relaxin acted within six hours, while progesterone took two to four days to produce the same effect. Estrogen seemed to be needed...
...roosters succulent, had been discovered by Biochemist Frederick W. Lorenz of the University of California. His method: the injection of a synthetic sex hormone. Lorenz had begun by wondering why a hen grows fat when it starts laying eggs. He proved it was because the female sex hormone, estrogen, increases the amount of fat in the blood. Lorenz then hit on the idea of giving estrogen (available in a cheap, synthetic form called diethylstilbestrol) to fatten up male fowl...