Word: estrogen
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...ESTROGEN REPRIEVE Many women facing menopause consider hormone-replacement therapy but fear that the estrogen in HRT will increase their risk of breast cancer. The jury is still out, but here's some reassurance. A study of 37,000 women found little evidence that estrogen is linked to common types of cancers such as ductal carcinoma in situ (a cancer confined to a duct). It may, however, increase some uncommon forms--but they are slow growing and may be easily treatable...
Medical research?s hunt for the perfect designer estrogen is getting hot. Ever since science has come to appreciate the good-news/bad-news equation associated with the natural female hormone -- it helps lower cholesterol and the risk of osteoporosis, but it may increase the risk of breast cancer -- researchers have been trying to come up with a better, synthetic substitute to help women in need of long-term hormone-replacement therapy after menopause. A new study published in Wednesday?s issue of the Journal of the American Medical Association suggests that scientists may have made a significant discovery about...
...This is the latest in a string of discoveries that indicate you can create chemicals that can act like estrogen in some parts of the body and as anti-estrogens in other parts of the body," says TIME medical columnist Christine Gorman. In the latest study, for example, the researchers found that raloxifene fits into the body?s estrogen receptors in such a way as to both increase bone density and block breast cancer. There are apparent side effects to raloxifene, however, such as an increased risk of blood clots. And there are also side effects to the other well...
Dream on. In a double-blind placebo-controlled trial of 20 men, published in last week's Journal of the American Medical Association, researchers from Iowa State University found that taking andro did nothing for testosterone levels. Instead, it boosted the amount of estrogen-like compounds in the blood and decreased levels of HDL, or "good" cholesterol, by 12%. Moreover, andro did not help test subjects build muscle mass at all. Scientists want to do more research to be sure, but right now it looks as though all that androstenedione consumed by would-be sluggers after McGwire broke the home...
...Since estrogen is known to protect the heart, it stood to reason that isoflavones might too. But when scientists fed purified isoflavones in pill form to test subjects, their cholesterol levels didn't budge. Now some researchers are focusing on the composition of the protein in soy to explain its potentially beneficial effects, while others argue that it's the combination of the protein and the isoflavones that does...