Word: estrogenic
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Dates: during 1960-1969
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...birds, DDT kills off the young by interfering with the female's egg-laying process. Though the exact chemistry is still obscure, the pesticide apparently sends the mother bird's liver into a frenzy of enzyme production. The excess enzymes break down such steroids as estrogen that are essential to the manufacture of calcium. Lacking adequate calcium, the bird's eggs emerge thin-shelled and flaky, offering scant protection for the embryo. In at least one instance, reports the National Audubon Society, which has just joined the public crusade against DDT, a bald-eagle egg was found...
...Pill on the U.S. market today contains two synthetic chemical components, one resembling the natural female hormone estrogen, the other a progestin that resembles progesterone, which women secrete chiefly during pregnancy. Some are combinations in which both the estrogen and the progestin are taken for 21 days a month; others are "sequentials," in which the estrogen alone is taken for 14 to 16 days, and estrogen with progestin for five...
...METABOLISM. Estrogens, but not progesterone, have long been known to influence the metabolism of fats-to the point where they have been given to men in the hope of lowering their blood-cholesterol levels and protecting them against heart attacks. In fact, says the University of Miami's Dr. William N. Spellacy, their effect on cholesterol is still debatable; they seem to increase the proportion of big, "flabby" fat molecules circulating in the blood. The most consistent finding, said Spellacy, is that increased estrogen levels cause increased blood levels of triglycerides, the complex, fat-containing molecules involved in atherosclerosis...
...estrogen component of the Pill is known to increase the coagulability of blood and therefore the risk of clot formation. British researchers have shown that women under 40 risk a clotting problem that is seven to nine times greater than the minuscule risk among nonpregnant women of the same age not on the Pill. Clots may form in either superficial or deep veins of the legs (thrombophlebitis), and may travel to the lungs, causing pulmonary embolism, which carries a high death rate. Or they may form in the brain, causing strokes. There are also a few cases in which...
...blood vessel bursts. Strokes are uncommon among women under 40, but several neurologists say they have seen as many as ten cases in a year among women on the Pill, where they used to see only one or two before the Pill. Both the increased blood pressure and the estrogen's effect on the clotting mechanism may be responsible. There are a few authenticated cases of severely impaired vision, even to the extent of blindness, as the result of clotting in the minute retinal arteries...