Word: estrogenic
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Dates: during 1970-1979
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Beginning in 1946, pregnant women with histories of spontaneous abortions were frequently treated with diethylstilbestrol, an artificial hormone. No one knows the number of miscarriages prevented by stilbestrol among the many thousands of women who took it; by 1960, questions about the estrogen compound's efficacy had induced most doctors to avoid it in treating pregnant women. But there is no doubt that in at least a handful of cases, daughters of women so treated have fallen victim to vaginal cancer. The mothers' use of stilbestrol is suspected of planting a hormonal time bomb that can be deadly...
...boys in Fellini's band. Still, if one cannot have pre-Christian Rome, contemporary London will do. Sunning himself in a graveyard one afternoon, Sloane is taken in-in every sense-by Kath (Beryl Reid). She is a bloated harpy who will never need silicone or estrogen. Enter two gentlemen who provide complications and multiply laughter. Kath's father Dadda (Alan Webb) is a senescent buzzard; her brother Ed (Harry Andrews) is a lantern-jawed caricature of muscle-bound Christianity...
Chlormadinone differs from conventional forms of the Pill in two vital respects: 1) it consists simply of a synthetic analogue of the hormone progesterone and contains none of the estrogen that has been implicated in clotting disorders among Pill users (TIME, Jan. 26); 2) it is taken every day of the year, and not on the 21-days-on, seven-days-off schedule of other forms of the Pill. Like the other versions-and, in fact, like all other potent medications-chlormadinone has its drawbacks. The failure rate, judged by unwanted pregnancies, is slightly higher than with other pills...
...other measures now under consideration could reduce the harmful effects still further. British research, cited repeatedly at Nelson's hearings, suggests that the risk of clotting is somewhat greater with the sequential pills. It is also directly related to the amount of estrogen in either type of Pill, and is markedly increased if the estrogen component is more than 50 micrograms (less than two millionths of an ounce). Britain has already officially discouraged the dispensing of pills with any higher estrogen content. By this reasoning, women in the U.S. would find themselves limited to seven...
...types are approved for general prescription: 1) 21 daily combination pills containing synthetic equivalents of the hormones progesterone and estrogen, with the latter in a microscopic dose; 2) sequential pills, which provide tablets of an estrogen alone for 14 to 16 days, followed by five to seven combination tablets. A third variety, the "one-everyday" pill of progestin (progesterone equivalent) only, is being tested but is not yet licensed for U.S. prescription...